CHEK1

About

Location: 11q24.2

Mappings

HGNC: HGNC:1925

Ensembl: NM_001114122.3

NCBI: ENSG00000149554

Refseq: 1111

Biomarkers

CHEK1 is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
CHEK1 pathogenic variants Germline Variant 1 1
CHEK1 oncogenic variants Somatic Variant 1 1

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) CHEK1 pathogenic variants Prostate Adenocarcinoma Olaparib
Sensitivity (+) CHEK1 oncogenic variants Prostate Adenocarcinoma Olaparib