ESR1

About

Location: 6q25.1-q25.2

Mappings

HGNC: HGNC:3467

Ensembl: NM_000125.4

NCBI: ENSG00000091831

Refseq: 2099

Biomarkers

ESR1 is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
ESR1 oncogenic variants Somatic Variant 1 2

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) ER positive, ESR1 oncogenic variants, HER2-negative Invasive Breast Carcinoma Elacestrant
Sensitivity (+) ER positive, ESR1 oncogenic variants, HER2-negative Invasive Breast Carcinoma Elacestrant