HRAS

About

Location: 11p15.5

Mappings

HGNC: HGNC:5173

Ensembl: NM_005343.4

NCBI: ENSG00000174775

Refseq: 3265

Biomarkers

HRAS is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
Wild type HRAS Wild type 5 5

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) Wild type HRAS, Wild type KRAS Colorectal Adenocarcinoma Fluorouracil, Oxaliplatin, Panitumumab
Sensitivity (+) Wild type HRAS, Wild type KRAS Colorectal Adenocarcinoma Panitumumab
Sensitivity (+) EGFR positive, Wild type HRAS, Wild type KRAS, Wild type NRAS Colorectal Adenocarcinoma Cetuximab
Sensitivity (+) EGFR positive, Wild type HRAS, Wild type KRAS, Wild type NRAS Colorectal Adenocarcinoma Cetuximab, Irinotecan
Sensitivity (+) EGFR positive, Wild type HRAS, Wild type KRAS, Wild type NRAS Colorectal Adenocarcinoma Cetuximab, Fluorouracil, Oxaliplatin