MET

About

Location: 7q31.2

Mappings

HGNC: HGNC:7029

Ensembl: ENSG00000105976

NCBI: 4233

Refseq: NM_000245.4

Biomarkers

MET is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
MET Exon 14 (Splice Site) Somatic Variant 2 5
MET Exon 14 (Deletion) Somatic Variant 2 5

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) MET Exon 14 (Splice Site) Non-Small Cell Lung Cancer Capmatinib
Sensitivity (+) MET Exon 14 (Deletion) Non-Small Cell Lung Cancer Capmatinib
Sensitivity (+) MET Exon 14 (Splice Site) Non-Small Cell Lung Cancer Tepotinib
Sensitivity (+) MET Exon 14 (Deletion) Non-Small Cell Lung Cancer Tepotinib
Sensitivity (+) MET Exon 14 (Splice Site) Non-Small Cell Lung Cancer Capmatinib
Sensitivity (+) MET Exon 14 (Deletion) Non-Small Cell Lung Cancer Capmatinib
Sensitivity (+) MET Exon 14 (Splice Site) Non-Small Cell Lung Cancer Tepotinib
Sensitivity (+) MET Exon 14 (Deletion) Non-Small Cell Lung Cancer Tepotinib
Sensitivity (+) MET Exon 14 (Splice Site) Non-Small Cell Lung Cancer Tepotinib
Sensitivity (+) MET Exon 14 (Deletion) Non-Small Cell Lung Cancer Tepotinib