Regulatory approval

Published by the Health Service Executive. Approved

Pertuzumab in combination with trastuzumab and vinorelbine for the treatment of adult patients with HER2- positive metastatic or locally recurrent unresectable breast cancer, who have not received previous anti- HER2 therapy or chemotherapy for their metastatic disease where patients are deemed clinically unsuitable for taxane based therapy

This is written in the approval document.

Reimbursement

Incomplete Reimbursement

Pertuzumab - ODMS; Trastuzumab, Vinorelbine - N/A

Citation

Pertuzumab, Trastuzumab, and Vinorelbine, 2024, version number 5, NCCP National SACT Regimen, NCCP, viewed 02/08/2026, https://healthservice.hse.ie/documents/6630/526_v5_Pertuzumab_Vinorelbine_trastuzumab_zOGbzKp.pdf

Therapeutic response

Precision oncology relationships for therapeutic response derived from this regulatory approval.

Organizations Biomarkers Cancer types Therapies
HSE (1) HER2-positive Invasive Breast Carcinoma Pertuzumab, Trastuzumab, Vinorelbine