Regulatory approval

Published by the Health Service Executive. Approved

Nivolumab in combination with platinum-based chemotherapy is indicated for the neoadjuvant treatment of resectable NSCLC at high risk of recurrence in adult patients whose tumours have PD-L1 expression >= 1%.

This is written in the approval document.

Reimbursement

Incomplete Reimbursement

Nivolumab - ODMS; Chemotherapy - N/A

Citation

Nivolumab 360mg and Chemotherapy, 2025, version number 2, NCCP National SACT Regimen, NCCP, viewed 26/03/2026, https://healthservice.hse.ie/documents/6865/849_V2_Nivolumab_chemotherapy.pdf

Therapeutic response

Precision oncology relationships for therapeutic response derived from this regulatory approval.

Organizations Biomarkers Cancer types Therapies
HSE (1) PD-L1 >= 1% Non-Small Cell Lung Cancer Carboplatin, Nivolumab, Paclitaxel
HSE (1) PD-L1 >= 1% Non-Small Cell Lung Cancer Carboplatin, Nivolumab, Pemetrexed
HSE (1) PD-L1 >= 1% Non-Small Cell Lung Cancer Cisplatin, Gemcitabine, Nivolumab
HSE (1) PD-L1 >= 1% Non-Small Cell Lung Cancer Carboplatin, Gemcitabine, Nivolumab
HSE (1) PD-L1 >= 1% Non-Small Cell Lung Cancer Cisplatin, Nivolumab, Pemetrexed