Regulatory approval

Published by the Health Service Executive. Approved

Induction of remission in newly diagnosed, previously untreated adult acute lymphoblastic leukaemia (ALL) patients (aged 25-65 years) treated on UKALL14-protocol.

This is written in the approval document.

Reimbursement

Incomplete Reimbursement

Imatinib - CDS; other drugs - N/A

Citation

UKALL14 Phase 1 Standard Induction Therapy, 2026, version number 1a, NCCP National SACT Regimen, NCCP, viewed 02/08/2026, https://healthservice.hse.ie/documents/7011/874_UKALL14_Phase_1_Standard_Induction_Therapy.pdf

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Therapeutic response

Precision oncology relationships for therapeutic response derived from this regulatory approval.

Organizations Biomarkers Cancer types Therapies
HSE (1) BCR::ABL1 Acute Lymphoid Leukemia Daunorubicin, Dexamethasone, Imatinib, Methotrexate, Vincristine
HSE (1) BCR::ABL1, CD20 + Acute Lymphoid Leukemia Daunorubicin, Dexamethasone, Imatinib, Methotrexate, Rituximab, Vincristine
HSE (1) CD20 + Acute Lymphoid Leukemia Daunorubicin, Dexamethasone, Methotrexate, Rituximab, Vincristine