Therapeutic Response Statement (Sensitivity)

This therapeutic response statement supports the relationship that ER negative, HER2-negative, PR negative status confers therapeutic sensitivity to Capecitabine in patients with Invasive Breast Carcinoma.

The Republic of Ireland's Health Service Executive (HSE) has approved capecitabine for reimbursement as a treatment option for the adjuvant treatment of stage I to IIIB triple negative breast cancer (TNBC) in patients with residual invasive disease after neoadjuvant chemotherapy treatment.

This statement is based on a regulatory approval from the Health Service Executive:

Adjuvant treatment of stage I to IIIB, triple negative breast cancer (TNBC) in patients with residual invasive disease after neoadjuvant chemotherapy treatment.

Citation

Capecitabine Monotherapy, 2023, version number 7, NCCP National SACT Regimen, NCCP, viewed 21/07/2024, https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/breast/216.pdf