EGFR oncogenic variants

About

Gene context: EGFR

Biomarker Type: Somatic Variant

Present: True

Chromosome: 7

Requires Oncogenic: True


Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings

Therapeutic response

Precision oncology relationships for therapeutic response involving this biomarker.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Erlotinib, Ramucirumab
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Gefitinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Afatinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Osimertinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Erlotinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Erlotinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Dacomitinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Afatinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Dacomitinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Osimertinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Gefitinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Erlotinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Erlotinib
Sensitivity (+) EGFR oncogenic variants Non-Small Cell Lung Cancer Bevacizumab, Erlotinib