EGFR p.T790M
About
Gene context: EGFR
Biomarker Type: Somatic Variant
Present: True
Chromosome: 7
Start Position: 55249071
End Position: 55249071
Reference Allele: C
Alternate Allele: T
Cdna Change: c.2369C>T
Protein Change: p.T790M
Variant Annotation: Missense
Exon: 20
Rsid: rs121434569
Hgvsg: 7:g.55249071C>T
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | EGFR p.T790M | Non-Small Cell Lung Cancer | Osimertinib | |
| Sensitivity (+) | EGFR p.T790M | Non-Small Cell Lung Cancer | Osimertinib | |
| Sensitivity (+) | EGFR p.T790M | Non-Small Cell Lung Cancer | Osimertinib |