EZH2 p.Y646C
About
Gene context: EZH2
Biomarker Type: Somatic Variant
Present: True
Chromosome: 7
Start Position: 148508727
End Position: 148508727
Reference Allele: T
Alternate Allele: C
Cdna Change: c.1937A>G
Protein Change: p.Y646C
Variant Annotation: Missense
Exon: 16/20
Rsid: rs267601394
Hgvsg: 7:g.148508727T>C
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | EZH2 p.Y646C | Follicular Lymphoma | Tazemetostat |