PTEN deletion
About
Gene context: PTEN
Biomarker Type: Copy Number
Present: True
Direction: Deletion
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | ER positive, HER2-negative, PTEN deletion | Invasive Breast Carcinoma | Capivasertib, Fulvestrant | |
| Sensitivity (+) | HER2-negative, PR positive, PTEN deletion | Invasive Breast Carcinoma | Capivasertib, Fulvestrant | |
| Sensitivity (+) | ER positive, HER2-negative, PR positive, PTEN deletion | Invasive Breast Carcinoma | Capivasertib, Fulvestrant | |
| Sensitivity (+) | ER positive, HER2-negative, PTEN deletion | Invasive Breast Carcinoma | Capivasertib, Fulvestrant |