RET p.M918T
About
Gene context: RET
Biomarker Type: Somatic Variant
Present: True
Chromosome: 10
Start Position: 43617416
End Position: 43617416
Reference Allele: T
Alternate Allele: C
Cdna Change: c.2753T>C
Protein Change: p.M918T
Variant Annotation: Missense
Exon: 16
Rsid: rs74799832
Hgvsg: 10:g.43617416T>C
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | RET p.M918T | Medullary Thyroid Cancer | Selpercatinib |