ABL1 p.T315I

Biomarker type: Somatic variant

Gene context: ABL1

HGVS.p: NP_005148.2:p.Thr315Ile

Precision oncology relationships for therapeutic response involving this biomarker.

Organizations	Biomarkers	Cancer types	Therapies
EMA (1) FDA (1)	ABL1 p.T315I, BCR::ABL1	Chronic Myelogenous Leukemia	Asciminib
FDA (1)	ABL1 p.T315I, BCR::ABL1	Acute Lymphoid Leukemia	Ponatinib
EMA (2) FDA (1) HSE (1)	ABL1 p.T315I	Chronic Myelogenous Leukemia	Ponatinib
EMA (1) HSE (1)	ABL1 p.T315I, not BCR::ABL1	Acute Lymphoid Leukemia	Ponatinib