Therapeutic Response Statement (Sensitivity)

This therapeutic response statement supports the relationship that EGFR oncogenic variants status confers therapeutic sensitivity to Gefitinib in patients with Non-Small Cell Lung Cancer.

The Republic of Ireland's Health Service Executive (HSE) has approved gefitinib monotherapy for reimbursement for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating mutations of EGFR-TK.

This statement is based on a regulatory approval from the Health Service Executive:

Treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating mutations of EGFR-TK

Citation

Gefitinib Monotherapy, 2020, version number 4, NCCP National SACT Regimen, NCCP, viewed 22/02/2024, https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/lung/220-gefitinib-monotherapy.pdf