Atezolizumab

About

Therapy type: Immunotherapy

Therapy strategy: PD-1/PD-L1 inhibition

Mappings

NCI Thesaurus: Atezolizumab (ncit:C106250)

RxNorm: atezolizumab (rxcui:1792776, omop:42629079)

SNOMED: Atezolizumab (sctid:719371003, omop:36714233)

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Therapeutic response

Precision oncology relationships for therapeutic response involving this therapy.

Organization(s)	Biomarker(s)	Cancer type	Therapy(ies)
FDA (1)	PD-L1 >= 1%	Non-Small Cell Lung Cancer	Atezolizumab
FDA (1)	PD-L1 >= 50%	Non-Small Cell Lung Cancer	Atezolizumab
FDA (1)	PD-L1 >= 10% TIIC	Non-Small Cell Lung Cancer	Atezolizumab
FDA (1)	Wild type ALK, Wild type EGFR	Non-Small Cell Lung Cancer	Atezolizumab, Bevacizumab, Carboplatin, Paclitaxel
FDA (1)	Wild type ALK, Wild type EGFR	Non-Small Cell Lung Cancer	Atezolizumab, Carboplatin, Paclitaxel
EMA (1) FDA (1) HSE (2)	EGFR somatic variants	Non-Small Cell Lung Cancer	Atezolizumab
EMA (1) FDA (1) HSE (2)	v::ALK	Non-Small Cell Lung Cancer	Atezolizumab
FDA (1)	BRAF p.V600E	Melanoma	Atezolizumab, Cobimetinib, Vemurafenib
FDA (1)	BRAF p.V600K	Melanoma	Atezolizumab, Cobimetinib, Vemurafenib
EMA (1) HSE (3)	PD-L1 >= 5%	Bladder Urothelial Carcinoma	Atezolizumab
EMA (2) HSE (6)	PD-L1 >= 50%, Wild type ALK, Wild type EGFR	Non-Small Cell Lung Cancer	Atezolizumab
EMA (1)	EGFR somatic variants	Non-Small Cell Lung Cancer	Atezolizumab, Bevacizumab, Carboplatin, Paclitaxel
EMA (1)	v::ALK	Non-Small Cell Lung Cancer	Atezolizumab, Bevacizumab, Carboplatin, Paclitaxel
EMA (1)	Wild type EGFR	Non-Small Cell Lung Cancer	Atezolizumab, Carboplatin, Nab-paclitaxel
EMA (1)	Wild type ALK	Non-Small Cell Lung Cancer	Atezolizumab, Carboplatin, Nab-paclitaxel
EMA (1)	Wild type ALK, Wild type EGFR	Non-Small Cell Lung Cancer	Atezolizumab, Carboplatin, Nab-paclitaxel
EMA (1) HSE (3)	PD-L1 >= 10% TIIC, Wild type ALK, Wild type EGFR	Non-Small Cell Lung Cancer	Atezolizumab
EMA (1) HSE (1)	ER negative, HER2-negative, PD-L1 >= 1%, PR negative	Invasive Breast Carcinoma	Atezolizumab, Nab-paclitaxel