Letrozole

About

Therapy type: Hormone therapy

Therapy strategy: Aromatase inhibition

Mappings

NCI Thesaurus: Letrozole (ncit:C1527)

RxNorm: letrozole (rxcui:72965, omop:4297547)

SNOMED: Letrozole (sctid:386911004, omop:1315946)

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Therapeutic response

Precision oncology relationships for therapeutic response involving this therapy.

Organization(s)	Biomarker(s)	Cancer type	Therapy(ies)
EMA (2) FDA (2) HSE (1)	ER positive, HER2-negative	Invasive Breast Carcinoma	Abemaciclib, Letrozole
EMA (2) FDA (2) HSE (1)	HER2-negative, PR positive	Invasive Breast Carcinoma	Abemaciclib, Letrozole
EMA (2) FDA (2) HSE (1)	ER positive, HER2-negative, PR positive	Invasive Breast Carcinoma	Abemaciclib, Letrozole
FDA (1)	ER positive, HER2-positive	Invasive Breast Carcinoma	Lapatinib, Letrozole
FDA (1)	HER2-positive, PR positive	Invasive Breast Carcinoma	Lapatinib, Letrozole
EMA (1) FDA (1)	ER positive, HER2-positive, PR positive	Invasive Breast Carcinoma	Lapatinib, Letrozole
EMA (1) FDA (1) HSE (1)	ER positive, HER2-negative	Invasive Breast Carcinoma	Letrozole, Palbociclib
EMA (1) FDA (1) HSE (1)	HER2-negative, PR positive	Invasive Breast Carcinoma	Letrozole, Palbociclib
EMA (1) FDA (1) HSE (1)	ER positive, HER2-negative, PR positive	Invasive Breast Carcinoma	Letrozole, Palbociclib
EMA (1) FDA (1) HSE (2)	ER positive, HER2-negative	Invasive Breast Carcinoma	Letrozole, Ribociclib
EMA (1) FDA (1) HSE (2)	HER2-negative, PR positive	Invasive Breast Carcinoma	Letrozole, Ribociclib
EMA (1) FDA (1) HSE (2)	ER positive, HER2-negative, PR positive	Invasive Breast Carcinoma	Letrozole, Ribociclib
EMA (1) FDA (1) HSE (1)	ER positive, HER2-negative	Invasive Breast Carcinoma	Goserelin, Letrozole, Ribociclib
EMA (1) FDA (1) HSE (1)	HER2-negative, PR positive	Invasive Breast Carcinoma	Goserelin, Letrozole, Ribociclib
EMA (1) FDA (1) HSE (1)	ER positive, HER2-negative, PR positive	Invasive Breast Carcinoma	Goserelin, Letrozole, Ribociclib
EMA (1)	ER positive, ERBB2 amplification, PR positive	Invasive Breast Carcinoma	Lapatinib, Letrozole
HPRA (3) HSE (3)	ER positive, PR positive	Invasive Breast Carcinoma	Letrozole
HPRA (3) HSE (3)	ER positive	Invasive Breast Carcinoma	Letrozole
HPRA (3) HSE (3)	PR positive	Invasive Breast Carcinoma	Letrozole
HPRA (1)	ER positive, HER2-negative	Invasive Breast Carcinoma	Letrozole
HPRA (1)	HER2-negative, PR positive	Invasive Breast Carcinoma	Letrozole
HPRA (1)	ER positive, HER2-negative, PR positive	Invasive Breast Carcinoma	Letrozole