IDH2 p.R140G
About
Gene context: IDH2
Biomarker Type: Somatic Variant
Present: True
Chromosome: 15
Start Position: 90631935
End Position: 90631935
Reference Allele: G
Alternate Allele: C
Cdna Change: c.418C>G
Protein Change: p.R140G
Variant Annotation: Missense
Exon: 4
Rsid: rs267606870
Hgvsg: 15:g.90631935G>C
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | IDH2 p.R140G | Acute Myeloid Leukemia | Enasidenib |