IDH2 p.R140Q
About
Gene context: IDH2
Biomarker Type: Somatic Variant
Present: True
Chromosome: 15
Start Position: 90631934
End Position: 90631934
Reference Allele: C
Alternate Allele: T
Cdna Change: c.419G>A
Protein Change: p.R140Q
Variant Annotation: Missense
Exon: 4
Rsid: rs121913502
Hgvsg: 15:g.90631934C>T
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | IDH2 p.R140Q | Acute Myeloid Leukemia | Enasidenib |