PDGFRA p.D842V
About
Gene context: PDGFRA
Biomarker Type: Somatic Variant
Present: True
Chromosome: 4
Start Position: 55152093
End Position: 55152093
Reference Allele: A
Alternate Allele: T
Cdna Change: c.2525A>T
Protein Change: p.D842V
Variant Annotation: Missense
Exon: 18
Rsid: rs121908585
Hgvsg: 4:g.55152093A>T
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | PDGFRA p.D842V | Gastrointestinal Stromal Tumor | Avapritinib | |
| Sensitivity (+) | PDGFRA p.D842V | Gastrointestinal Stromal Tumor | Avapritinib |