TP53 somatic variants
About
Gene context: TP53
Biomarker Type: Somatic Variant
Present: True
Chromosome: 17
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | TP53 somatic variants | Chronic Lymphocytic Leukemia | Venetoclax | |
| Sensitivity (+) | TP53 somatic variants | Chronic Lymphocytic Leukemia | Idelalisib, Rituximab | |
| Sensitivity (+) | TP53 somatic variants | Chronic Lymphocytic Leukemia | Venetoclax | |
| Sensitivity (+) | TP53 somatic variants | Chronic Lymphocytic Leukemia | Zanubrutinib | |
| Sensitivity (+) | TP53 somatic variants | Chronic Lymphocytic Leukemia | Acalabrutinib | |
| Sensitivity (+) | TP53 somatic variants | Chronic Lymphocytic Leukemia | Ibrutinib | |
| Sensitivity (+) | TP53 somatic variants | Chronic Lymphocytic Leukemia | Idelalisib, Rituximab | |
| Sensitivity (+) | TP53 somatic variants | Chronic Lymphocytic Leukemia | Idelalisib, Ofatumumab |