Ivosidenib

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Therapy type: Targeted therapy

Therapy strategy: IDH1 inhibition

Mappings

NCI Thesaurus: Ivosidenib (ncit:C114383)

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Therapeutic response

Precision oncology relationships for therapeutic response involving this therapy.

Type	Biomarker(s)	Cancer type	Therapy(ies)
Sensitivity (+)	IDH1 p.R132C	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132G	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132H	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132L	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132S	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132C	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132G	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132H	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132L	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132S	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132C	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132G	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132H	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132L	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132S	Acute Myeloid Leukemia	Ivosidenib
Sensitivity (+)	IDH1 p.R132C	Myelodysplastic Syndromes	Ivosidenib
Sensitivity (+)	IDH1 p.R132G	Myelodysplastic Syndromes	Ivosidenib
Sensitivity (+)	IDH1 p.R132H	Myelodysplastic Syndromes	Ivosidenib
Sensitivity (+)	IDH1 p.R132L	Myelodysplastic Syndromes	Ivosidenib
Sensitivity (+)	IDH1 p.R132S	Myelodysplastic Syndromes	Ivosidenib
Sensitivity (+)	IDH1 p.R132C	Cholangiocarcinoma	Ivosidenib
Sensitivity (+)	IDH1 p.R132G	Cholangiocarcinoma	Ivosidenib
Sensitivity (+)	IDH1 p.R132H	Cholangiocarcinoma	Ivosidenib
Sensitivity (+)	IDH1 p.R132L	Cholangiocarcinoma	Ivosidenib
Sensitivity (+)	IDH1 p.R132S	Cholangiocarcinoma	Ivosidenib
Sensitivity (+)	IDH1 p.R132C	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132G	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132H	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132L	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132S	Acute Myeloid Leukemia	Azacitidine, Ivosidenib
Sensitivity (+)	IDH1 p.R132C	Cholangiocarcinoma	Ivosidenib
Sensitivity (+)	IDH1 p.R132G	Cholangiocarcinoma	Ivosidenib
Sensitivity (+)	IDH1 p.R132H	Cholangiocarcinoma	Ivosidenib
Sensitivity (+)	IDH1 p.R132L	Cholangiocarcinoma	Ivosidenib
Sensitivity (+)	IDH1 p.R132S	Cholangiocarcinoma	Ivosidenib